Collagenex 2™

Collagen Support Supplement

Therapeutic Actions

·         Reduces joint pain and stiffness in 7-10 days (supported by clinical trials).

·         Treats osteoarthritis, rheumatoid arthritis, lupus, fibromyalgia, tendonitis/

tendon weakness, back pain, and other connective tissue disorders.

·         Clinically proven to improve joint health and flexibility faster than any

other joint healing ingredients with one capsule per day dosing.

Administration

Internal: 1 capsule per day

60 capsules, 500mg

Contraindications: Egg allergy

Ingredients

·         Eggshell membrane (NEMR)

Other Ingredients: Hypromellose (vegetable cellulose) and rice bran.

Contains egg.

Formula Rationale

There are many approaches to treating joint pain and stiffness. Whereas the long-term safety

of analgesic drugs has not been established, complementary and alternative therapies tend

to work slowly. Seniors and other populations take these products in the dosages required for

improvement. Collagenex 2 is the next generation joint supplement. It supports the joints and

connective tissues and reduces pain in seven to ten days at a dosage of one capsule per day.

Collagenex 2 is a patented ingredient containing collagen, glycosaminoglycans such as

chondroitin sulfate, glucosamine, hyaluronic acid, and enzymes, which support the joints

and connective tissue. Connective tissue is the material inside your body that supports

many of its parts. It is the "cellular glue", that gives your tissues their shape and helps keep

them strong.

Initially two pilot studies were conducted to evaluate efficacy for the relief of pain and

discomfort associated with joint and connective tissue disorders. Based upon the positive

results from the initial studies, a follow up eight-week randomized, multicenter double-blind

placebo-controlled trial was conducted to evaluate relief of pain and stiffness associated with

moderate osteoarthritis (OA) of the knee compared to a placebo. The primary treatment

response endpoints were the 10, 30, and 60-day clinical assessments utilizing the WOMAC

(Western Ontario and McMaster University) Osteoarthritis index. The version used in the study

consists of five questions addressing the severity of joint pain, two questions addressing joint

stiffness, and seventeen questions addressing function.

In the first clinical trial subjects were enrolled with various joint and connective tissue

conditions. Results of the first clinical trial revealed the formula improved flexibility by 27.8

percent in seven days and at thirty days reduced general pain 72.5 percent, increased flexibility

43.7 percent, and range of motion pain was reduced 75.9 percent. Compliance was greater

than 98 percent.

In the double arm pilot trial, twenty-six subjects were enrolled with various joint and connective

tissue conditions. Statistical analysis of the primary outcome measurements revealed that the

formula produced a rapid treatment response for pain at seven days. The treatment response

continued through 30 days for pain with a 30.2 percent pain reduction.

In the placebo-controlled trial a total of sixty-seven subjects were enrolled. An analysis for the

primary outcome measurements revealed that supplementation with the formula yielded a

15.9 percent reduction in pain, a 12.8 percent reduction in mean stiffness after ten days of

supplementation, which were maintained at 60 days.

To summarize, one third of patients experienced a greater than 30 percent pain reduction in

10 days. Nearly one third of patients experienced a greater than 50 percent reduction in pain

in sixty days. One fourth of patients experienced a greater than 50 percent reduction in stiffness

in 60 days. Collagenex 2 possesses natural anti-inflammatory properties and is a natural source

of chondroitin sulfate, hyaluronic acid, and collagen essential for healthy joints. It is

manufactured in the USA.

Cold Away can be taken with Clear Air if there is more chest involvement. Cold Away is only used in acute stages of externally contracted illness. It is not used for prevention of colds and flu on long-term basis.

Additional Formulas

·         Combine with Mobility 2 for joint pain and swelling resulting from stagnant Qi and blood.

Joint may feel hot to the touch.

·         Combine with Mobility 3 when pain worsens suddenly with activity or cold, damp weather.

·         Combine with AC-Q for lower body joint and muscle pain that may result from injury, when

the discomfort is accompanied by weakness.